diff --git a/src/dev-app/menu/menu-demo.html b/src/dev-app/menu/menu-demo.html
index d4cc3801ed01..6f42f60caa10 100644
--- a/src/dev-app/menu/menu-demo.html
+++ b/src/dev-app/menu/menu-demo.html
@@ -105,9 +105,7 @@
     </mat-menu>
   </div>
   <div class="demo-menu-section">
-    <p>
-      Position x: before
-    </p>
+    <p>Position x: before</p>
     <mat-toolbar class="demo-end-icon">
       <button matIconButton [matMenuTriggerFor]="posXMenu" aria-label="Open x-positioned menu">
         <mat-icon>more_vert</mat-icon>
@@ -124,9 +122,7 @@
     </mat-menu>
   </div>
   <div class="demo-menu-section">
-    <p>
-      Position y: above
-    </p>
+    <p>Position y: above</p>
     <mat-toolbar>
       <button matIconButton [matMenuTriggerFor]="posYMenu" aria-label="Open y-positioned menu">
         <mat-icon>more_vert</mat-icon>
@@ -158,9 +154,7 @@
     </mat-menu>
   </div>
   <div class="demo-menu-section">
-    <p>
-      Position x: before, overlapTrigger: true
-    </p>
+    <p>Position x: before, overlapTrigger: true</p>
     <mat-toolbar class="demo-end-icon">
       <button matIconButton [mat-menu-trigger-for]="posXMenuOverlay">
         <mat-icon>more_vert</mat-icon>
@@ -177,9 +171,7 @@
     </mat-menu>
   </div>
   <div class="demo-menu-section">
-    <p>
-      Position y: above, overlapTrigger: true
-    </p>
+    <p>Position y: above, overlapTrigger: true</p>
     <mat-toolbar>
       <button matIconButton [mat-menu-trigger-for]="posYMenuOverlay">
         <mat-icon>more_vert</mat-icon>
@@ -192,6 +184,39 @@
       }
     </mat-menu>
   </div>
+  <div class="demo-menu-section">
+    <p>disabledInteractive (should not open)</p>
+    <mat-toolbar>
+      <button
+        disabled
+        [disabledInteractive]="true"
+        matIconButton
+        [mat-menu-trigger-for]="disabledInteractiveMenu"
+      >
+        <mat-icon>more_vert</mat-icon>
+      </button>
+    </mat-toolbar>
+
+    <mat-menu #disabledInteractiveMenu="matMenu">
+      @for (item of items; track item) {
+        <button mat-menu-item [disabled]="item.disabled">{{ item.text }}</button>
+      }
+    </mat-menu>
+  </div>
+  <div class="demo-menu-section">
+    <p>vanilla button disabled binding</p>
+    <mat-toolbar>
+      <button [disabled]="true" [mat-menu-trigger-for]="disabledInteractiveMenu">
+        <mat-icon>more_vert</mat-icon>
+      </button>
+    </mat-toolbar>
+
+    <mat-menu #disabledInteractiveMenu="matMenu">
+      @for (item of items; track item) {
+        <button mat-menu-item [disabled]="item.disabled">{{ item.text }}</button>
+      }
+    </mat-menu>
+  </div>
 </div>
 
 <div class="demo-context-menu-area" [matContextMenuTriggerFor]="contextMenu">
diff --git a/src/material/menu/BUILD.bazel b/src/material/menu/BUILD.bazel
index 4fb81fba46b5..9b8ab63420f1 100644
--- a/src/material/menu/BUILD.bazel
+++ b/src/material/menu/BUILD.bazel
@@ -111,6 +111,7 @@ ng_project(
         "//src/cdk/overlay",
         "//src/cdk/scrolling",
         "//src/cdk/testing/private",
+        "//src/material/button",
         "//src/material/core",
     ],
 )
diff --git a/src/material/menu/menu-trigger-base.ts b/src/material/menu/menu-trigger-base.ts
index efdf997a3b88..1519ceeccd4d 100644
--- a/src/material/menu/menu-trigger-base.ts
+++ b/src/material/menu/menu-trigger-base.ts
@@ -22,6 +22,7 @@ import {
 } from '@angular/cdk/overlay';
 import {TemplatePortal} from '@angular/cdk/portal';
 import {
+  booleanAttribute,
   ChangeDetectorRef,
   Directive,
   ElementRef,
@@ -191,6 +192,10 @@ export abstract class MatMenuTriggerBase implements OnDestroy {
 
   /** Internal method to open menu providing option to auto focus on first item. */
   protected _openMenu(autoFocus: boolean): void {
+    if (this._triggerIsAriaDisabled()) {
+      return;
+    }
+
     const menu = this._menu;
 
     if (this._menuOpen || !menu) {
@@ -477,4 +482,12 @@ export abstract class MatMenuTriggerBase implements OnDestroy {
   private _ownsMenu(menu: MatMenuPanel): boolean {
     return PANELS_TO_TRIGGERS.get(menu) === this;
   }
+
+  /**
+   * Detect if the trigger element is aria-disabled, indicating it should behave as
+   * disabled and not open the menu.
+   */
+  private _triggerIsAriaDisabled() {
+    return booleanAttribute(this._element.nativeElement.getAttribute('aria-disabled'));
+  }
 }
diff --git a/src/material/menu/menu.spec.ts b/src/material/menu/menu.spec.ts
index 28a0d50fd10e..14c1ecb99d97 100644
--- a/src/material/menu/menu.spec.ts
+++ b/src/material/menu/menu.spec.ts
@@ -42,6 +42,7 @@ import {
   provideFakeDirectionality,
 } from '../../cdk/testing/private';
 import {MATERIAL_ANIMATIONS, MatRipple} from '../core';
+import {MatButton} from '@angular/material/button';
 import {MatMenu, MatMenuItem} from './index';
 import {
   MAT_MENU_DEFAULT_OPTIONS,
@@ -1279,6 +1280,23 @@ describe('MatMenu', () => {
     }));
   });
 
+  it('does not open if the trigger element is disabled (including disabledInteractive)', fakeAsync(() => {
+    const fixture = TestBed.createComponent(DisabledMenu);
+    fixture.detectChanges();
+
+    const trigger = fixture.componentInstance.triggerEl.nativeElement;
+    trigger.click();
+    fixture.detectChanges();
+    tick(500);
+    expect(overlayContainerElement.querySelector('.mat-mdc-menu-panel [mat-menu-item]')).toBeNull();
+
+    dispatchKeyboardEvent(trigger, 'keydown', ENTER);
+    trigger.click();
+    fixture.detectChanges();
+    tick(500);
+    expect(overlayContainerElement.querySelector('.mat-mdc-menu-panel [mat-menu-item]')).toBeNull();
+  }));
+
   describe('positions', () => {
     let fixture: ComponentFixture<PositionedMenu>;
     let trigger: HTMLElement;
@@ -2634,6 +2652,20 @@ class SimpleMenu {
 })
 class SimpleMenuOnPush extends SimpleMenu {}
 
+@Component({
+  template: `
+    <button mat-button disabled [disabledInteractive]="true"
+        [matMenuTriggerFor]="menu" #triggerEl>Toggle menu</button>
+    <mat-menu #menu="matMenu">
+      <button mat-menu-item> Action! </button>
+    </mat-menu>
+  `,
+  imports: [MatButton, MatMenuTrigger, MatMenu, MatMenuItem],
+})
+class DisabledMenu {
+  @ViewChild('triggerEl', {read: ElementRef}) triggerEl!: ElementRef<HTMLElement>;
+}
+
 @Component({
   template: `
     <button [matMenuTriggerFor]="menu" #triggerEl>Toggle menu</button>
@@ -2666,7 +2698,7 @@ interface TestableMenu {
 class OverlapMenu implements TestableMenu {
   @Input() overlapTrigger: boolean = false;
   @ViewChild(MatMenuTrigger) trigger!: MatMenuTrigger;
-  @ViewChild('triggerEl') triggerEl!: ElementRef<HTMLElement>;
+  @ViewChild('triggerEl', {read: ElementRef}) triggerEl!: ElementRef<HTMLElement>;
 }
 
 @Component({