diff --git a/changelog.md b/changelog.md
index 520a9614..b1d548fc 100644
--- a/changelog.md
+++ b/changelog.md
@@ -22,6 +22,7 @@ Features
 * Add `/help` prompt to initial toolbar help.
 * Advertise forward-slash `/command` forms in `/help` output.
 * Override `min_completion_trigger` for the `/command` form.
+* Accept DSN schemes with `+` sign.
 
 
 Bug Fixes
diff --git a/mycli/packages/cli_utils.py b/mycli/packages/cli_utils.py
index d90575db..482348ce 100644
--- a/mycli/packages/cli_utils.py
+++ b/mycli/packages/cli_utils.py
@@ -24,7 +24,10 @@ def is_valid_connection_scheme(text: str) -> tuple[bool, str | None]:
     if "://" not in text:
         return False, None
     scheme = text.split("://")[0]
-    if scheme not in ("mysql", "mysqlx", "tcp", "socket"):
-        return False, scheme
-    else:
+    if scheme.startswith('mysql+'):
         return True, None
+    if scheme.startswith('mysqlx+'):
+        return True, None
+    if scheme in ("mysql", "mysqlx", "tcp", "socket"):
+        return True, None
+    return False, scheme
diff --git a/test/pytests/test_cli_runner.py b/test/pytests/test_cli_runner.py
index 5c2ae740..4adba139 100644
--- a/test/pytests/test_cli_runner.py
+++ b/test/pytests/test_cli_runner.py
@@ -337,6 +337,20 @@ def test_run_from_cli_args_rejects_unknown_alias_dsn_scheme(monkeypatch: pytest.
     ]
 
 
+def test_run_from_cli_args_accepts_mysql_plus_dsn_scheme(monkeypatch: pytest.MonkeyPatch) -> None:
+    cli_args = make_cli_args()
+    cli_args.dsn = 'mysql+pymysql://user:pass@host:3306/db'
+    client = DummyMyCli()
+
+    run_with_client(monkeypatch, cli_args, client)
+
+    assert client.connect_calls[-1]['user'] == 'user'
+    assert client.connect_calls[-1]['passwd'] == 'pass'
+    assert client.connect_calls[-1]['host'] == 'host'
+    assert client.connect_calls[-1]['port'] == 3306
+    assert client.connect_calls[-1]['database'] == 'db'
+
+
 def test_run_from_cli_args_maps_dsn_ssl_parameters(monkeypatch: pytest.MonkeyPatch) -> None:
     cli_args = make_cli_args()
     cli_args.dsn = (
diff --git a/test/pytests/test_cli_utils.py b/test/pytests/test_cli_utils.py
index 9a921214..01fa66ae 100644
--- a/test/pytests/test_cli_utils.py
+++ b/test/pytests/test_cli_utils.py
@@ -35,7 +35,9 @@ def test_filtered_sys_argv_appends_empty_password_sentinel(monkeypatch, password
     [
         ('localhost', False, None),
         ('mysql://user@localhost/db', True, None),
+        ('mysql+pymysql://user@localhost/db', True, None),
         ('mysqlx://user@localhost/db', True, None),
+        ('mysqlx+pymysql://user@localhost/db', True, None),
         ('tcp://localhost:3306', True, None),
         ('socket:///tmp/mysql.sock', True, None),
         ('ssh://user@example.com', False, 'ssh'),