WARNING: I'm not 100% sure about this. So please excuse me if this issue was a mistake/is wrong.
As far as I have understood it, as of version 4.0 of Pi-hole there is no need to execute the iptables commands listet in the "Blocking Https Advertisement Assets" section here.
Reason as to why I think this is an issue: The edit "Update: 2018-08-06" in the top post